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The Impact of De-implementing Urine Dipsticks for Diagnosis of UTIs in Hospitals

StatusNot Yet Recruiting
PhaseNot specified
Started
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Record status
This record was last updated October 1, 2025 (before its estimated June 2026 completion). Its status may not reflect the trial's current state.

Record History

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  1. Notable Primary completion date: Oct 2025 to Jun 2026
    • Start date: Apr 2025 to Dec 2025
    • Study completion date: Jan 2026 to Dec 2026
    v3
  2. Minor Eligibility criteria shortened, about 9 words
    • Study description expanded, about 2 words
    v2
  3. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The goal of this interrupted time-series analysis is to evaluate the impact of the de-implementation of urine dipsticks as a diagnostic tool for urinary tract infections (UTIs) in hospitalized patients in the North Denmark Region. The main question it aims to answer is: How does de-implementation of urine dipsticks affect the diagnosis and management of UTIs and related disorders? Specifically, does it change the following parameters: * Number and severity of UTI infections (lower and upper UTI, non-severe and severe) * Antibiotic prescription (overall, antibiotic classes, administration routes, duration, dosages) * Number of urine cultures and number of positive urine cultures * Risks of admission to intensive care units and 30-day mortality * Risk of drug toxicity * Length of hospital stay * Risk of admission to intensive care unit * 30-day risk of readmission after discharge * 6-month risks of Clostridioides difficile enterocolitis and de novo antimicrobial resistance in cultures obtained during routine clinical care. Researchers hypothesize that de-implementing urine dipsticks will lead to a reduced frequency of diagnosed cystitis, reduced antibiotic use, and fewer urine cultures without negatively affecting patient mortality or readmission risk. Researchers will compare the outcomes before and after the discontinuation of urine dipsticks across hospitals in the North Denmark Region. Furthermore, results will be compared to another Danish administrative healthcare region where dipsticks are still in use as well as urine culture data from the primary sector in the North Denmark Region. Since this is a registry-based observational study utilizing data from the electronic patient record system in the North Denmark Region, no direct contact will be made with participants.
Trial Details
NCT Number NCT06750666
Lead Sponsor Jacob Bodilsen
Conditions
(from sponsor)
Urinary Tract Infections, Diagnostic Techniques and Procedures, Point-of-Care Testing, Anti-Bacterial Agents, Registry, Clinical Decision-making, Urinalysis
Related terms Urinary Tract Infections
Enrollment 480,000 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov