Examining the Effects of Different Resistive Exercise Programs in Individuals With Compensated Liver Cirrhosis

Reasons such as sleep disorders, depression, decreased independence in daily living activities and decreased quality of life, which are seen in the majority of liver cirrhosis patients, can cause cognitive dysfunction, especially attention. It is known that physical dysfunctions are observed in patients with liver cirrhosis along with cognitive dysfunction. Sarcopenia is the most important of these dysfunctions. Sarcopenia is the progressive, widespread loss of muscle mass, function and strength. The aim of this study is to determine the effects of face-to-face and home-based progressive strengthening exercise program performed 3 times a week for 12 weeks on muscle strength, muscle mass, functionality and cognitive functions in individuals with liver cirrhosis. It is also aimed to test the feasibility and effectiveness of the home-based exercise method in individuals with liver cirrhosis. Another aim of our study is to determine the exercise dose required to improve muscle strength, muscle mass, functionality and cognitive functions in individuals with liver cirrhosis and the duration of treatment effectiveness through follow-up.

NCT Number	NCT06749340
Lead Sponsor	Bahçeşehir University
Conditions	Coginitive Dysfunction, Compensated Liver Cirrhosis, Physical Dysfunction, Sarcopenia
Enrollment	20 participants
Start Date	2026-02-19
Primary Completion	2026-12-23 (estimated)
Study Completion	2026-12-23 (estimated)
Updated on ClinicalTrials.gov	2026-02-20