Clinical Trial

Drug-Eluting Balloon or Drug-Eluting Stent in Acute Myocardial Infarction: A Randomized Controlled Trial

Study acronym: BOOST-AMI
Recruiting
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Summary
The objective of the study is to compare drug-coated balloon (DCB) with the gold standard drug-eluting stent (DES) in percutaneous coronary intervention (PCI) for patients presenting with ST-elevation myocardial infarction (STEMI). Randomization will be performed after successful culprit-lesion preparation and confirmation that all angiographic entry criteria are met. Patients will be randomly assigned in a 1:1 fashion to receive either treatment with a Paclitaxel-coated balloon alone or second or third-generation DES.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2024-12-19; most recent amendment 2026-03-25.
Status change: Active, Not Recruiting → Recruiting 2025-03-30
Trial Details
NCT Number NCT06746233
Lead Sponsor Institute of Cardiovascular Diseases, Vojvodina
Conditions ST Elevation Myocardial Infarction (STEMI)
Enrollment 598 participants
Start Date 2024-12-25
Primary Completion 2028-12 (estimated)
Study Completion 2028-12 (estimated)
Updated on ClinicalTrials.gov 2026-03-30