Clinical Trial

Disentangling the Effects of Daily Stress, Sleep, and Sex Hormones on Accelerated Vascular Aging in Midlife Women

Study acronym: V-RISES
Recruiting Phase 4
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Summary
The purpose of this study is to identify the impact of estradiol (E2) on the associations between (a) responsivity to daily stress or (b) sleep variability with vascular function in midlife premenopausal women.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2024-12-17; most recent amendment 2026-07-01.
Trial Details
NCT Number NCT06745466
Lead Sponsor University of Delaware
Collaborators: National Institute on Aging (NIA)
Conditions Estrogen, Premenopause
Enrollment 30 participants
Start Date 2024-11-15
Primary Completion 2026-10-31 (estimated)
Study Completion 2027-10 (estimated)
Updated on ClinicalTrials.gov 2026-07-02