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Effects of Including Interferential Current in a Therapeutic Exercise Program in Individuals With Knee Osteoarthritis

StatusRecruiting
PhaseNot applicable
Started
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Record status
This record was last updated May 22, 2026 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.

Record History

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  1. Notable Trial status changed: Active, Not Recruiting → Recruiting
    • Primary completion pushed from Apr 30, 2026 to Jun 30, 2026
    • Study completion pushed from May 28, 2026 to Jul 28, 2026
    • Site details revised
    v5
  2. Notable Primary completion date: Dec 20, 2027 to Apr 30, 2026v4 Show 7 more changesShow less
    • Primary endpoint revised
    • Trial status: Recruiting to Active, Not Recruiting
    • Enrollment target: estimated 126 to confirmed 138
    • Study completion date: Jan 20, 2028 to May 28, 2026
    • Secondary endpoints: 6 to 7
    • Study description expanded, about 166 words
    • Site details revised
  3. Notable Trial status: Not Yet Recruiting to Recruiting
    • Site details revised
    v3
  4. Minor Secondary endpoints: details revised at 2 of 6 entries
    • Study title revised
    v2
  5. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The first-line treatment for knee osteoarthritis (KOA) in terms of pain and functionality is physical exercise. The use of interferential current (IC) associated with other resources may be beneficial in reducing pain intensity and improving functionality. However, the effects of its simultaneous use with therapeutic exercise have not yet been fully established. The aim of this project will be to evaluate the effects of including IC in a therapeutic exercise program in relation to pain intensity, functionality, self-efficacy, maximum voluntary contraction and overall perceived effect in individuals with KOA. Therefore, research participants of both sexes, between 40 and 75 years old, with a clinical diagnosis of unilateral KOA, who have knee pain for more than 3 months, with a minimum score of 3 points on the numerical pain scale, morning stiffness for less than 30 minutes, crepitation, bone sensitivity, and absence of palpable heat will be recruited. The research participants will be randomized into three groups: therapeutic exercises (n=46) and therapeutic exercises + IC (n=46) and therapeutic exercises + IC placebo (n=46). Eight consecutive weeks of treatment will be carried out. The research participants will be evaluated before the intervention, after the end of the intervention of eight consecutive weeks of intervention and after four weeks at the end of the last week of intervention, through the instruments: numeric pain scale (NPS), Knee Injury and Osteoarthritis Outcome Score (KOOS), patient-specific functional scale (EFEP), Pain self-efficacy questionnaire (PSEQ), maximum voluntary isometric contraction (MVIC), 30-second sit-to-stand test (TSL30s), global perception scale (EPG). For data analysis, a normality test will be used to verify the distribution of the data and a statistical test appropriate for the appropriate intra and inter-group comparisons, thus considering two factors in the comparisons, time and group. A significance level of 5% will be adopted.
Trial Details
NCT Number NCT06744036
Lead Sponsor University of Nove de Julho
Conditions
(from sponsor)
Osteoarthritis, Knee
Related terms Osteoarthritis, Knee
Enrollment 138 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov