Clinical Trial

Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections

Study acronym: TREMO-Pemba
Active, Not Recruiting Phase 3
View on ClinicalTrials.gov →
Summary
This study aims to assess the efficacy and safety of emodepside compared to mebendazole in adults and adolescents infected with T. trichiura, either as single infection or co-infections with hookworm and/or A. lumbricoides.
Protocol Amendment History 3 changes
critical Trial status changed: Enrolling by Invitation → Active, Not Recruiting 2026-08-15
notable Primary completion pushed: 2026-05 -> 2026-07 2026-05-15
minor Completion pushed: 2026-07 -> 2026-10 2026-05-15
Trial Details
NCT Number NCT06736691
Lead Sponsor Swiss Tropical & Public Health Institute
Collaborators: Public Health Laboratory Ivo de Carneri, Bayer, Coefficient Giving (Formerly Open Philanthropy), Ifakara Health Institute
Conditions Trichuris Trichiura; Infection, Hookworm Infection, Ascaris Lumbricoides Infection
Enrollment 315 participants
Start Date 2025-11-25
Primary Completion 2026-07-01 (estimated)
Study Completion 2026-09-16 (estimated)
Updated on ClinicalTrials.gov 2026-08-14