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Nicotinamide Supplementation in Glaucoma

Study acronym: TAMING
StatusEnrolling by Invitation
PhasePhase 3
Started
View on ClinicalTrials.gov ↗

Record History

  1. Study First Submitted
The goal of this clinical trial is to learn if nicotinamide (NAM, vitamin B3) supplementation can delay glaucoma progression 30% above that achieved with conventional glaucoma treatment using topical medication. The main questions it aims to answer are: Can NAM supplementation improve the visual function of patients with glaucoma measured by visual field perimetry? Researchers will compare NAM to a placebo (a look-alike substance that contains no drug) to see if NAM works as an adjuvant in glaucoma treatment. Participants will: * Take NAM or a placebo every day for 2 years * Visit the clinic once every 3-4 months for checkups and tests
Trial Details
NCT Number NCT06731582
Lead Sponsor Singapore Eye Research Institute
Collaborators: National University Hospital, Singapore, Singapore National Eye Centre
Conditions
(from sponsor)		 Glaucoma
Related terms Glaucoma
Enrollment 520 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov