Clinical Trial

EGM Guided PFA for PerAF

Study acronym: EGM-PFA
Active, Not Recruiting
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Record status
This record was last updated June 4, 2025 (before its estimated December 1, 2025 completion). Its status may not reflect the trial's current state.
Summary
Pulse field ablation (PFA) has shown safety and efficacy in paroxysmal atrial fibrillation (AF), while the application in persistent atrial fibrillation (PerAF) is still under investigation. The investigators' previous randomized controlled trial showed favorable outcomes with electrogram (EGM) guided radiofrequency ablation in PerAF. However, EGM-guided PFA has not yet been reported.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2024-12-09; most recent amendment 2025-05-29.
Trial Details
NCT Number NCT06729866
Lead Sponsor Xu Liu
Conditions Persistent Atrial Fibrillation
Enrollment 58 participants
Start Date 2024-09-20
Primary Completion 2025-12-01 (estimated)
Study Completion 2025-12-01 (estimated)
Updated on ClinicalTrials.gov 2025-06-04