Nissen Versus Dor Hiatal Hernia Repair

Hiatal hernia can present with a wide range of symptoms. An usual surgical repair technique usually includes Nissen fundoplication, while other procedures are less frequently employed. However, recurrence and reoperation rates remain high. This randomized controlled trial aims to compare the efficacy of Nissen and Dor fundoplication in preventing hiatal hernia recurrence and reducing the risk of reoperation Participants undergoing minimally invasive hiatal hernia repair will be randomly assigned to either Nissen or Dor fundoplication. Postoperatively at 12 months, anatomical recurrence rates based on computed tomography scans and symptomatic recurrence rates, anti-reflux medication use, GERD-related quality of life, and dysphagia symptoms will be assessed. A subsequent long-term follow-up study will conducted afterwards utilizing national registry data to evaluate reoperation rates and anti-reflux medication use

NCT Number	NCT06725433
Lead Sponsor	Kuopio University Hospital
Conditions	Hiatal Hernia, Paraesophageal Hernia, Recurrence
Enrollment	150 participants
Start Date	2025-02-07
Primary Completion	2030-01-30 (estimated)
Study Completion	2030-01-30 (estimated)
Updated on ClinicalTrials.gov	2025-02-19