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Taurine Supplementation in Long COVID

StatusRecruiting
PhasePhase 2/3
Started
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Record History

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  1. Notable Primary endpoints: details revised at 1 of 2 entries
    • Eligibility criteria expanded, about 15 words
    • Secondary endpoints: details revised at 1 of 14 entries
    • Site details revised at 2 of 5 sites
  2. Minor Site details revised at 1 of 5 sitesv7
  3. Minor Site details revised at 1 of 5 sitesv6
  4. Minor Study sites: 4 to 5v5
  5. Notable Trial status: Not Yet Recruiting to Recruiting
    • Study sites: 1 to 4
    • Start date changed from estimate of Oct 2025 to Nov 18, 2025
    v4
Show 2 earlier versionsHide 2 earlier versions
  1. Notable Start date: Jun 2025 to Oct 2025v3
  2. Notable Start date: Feb 2025 to Jun 2025
    • Primary endpoints: 1 to 2
    • Study sites: 0 to 1
    • Secondary endpoints revised (14)
    v2
  1. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The COVID-19 pandemic has swept across the globe, affecting millions of individuals with varying degrees of severity. While many individuals recover from the acute phase of the infection, a significant proportion continue to experience persistent and debilitating symptoms long after the initial SARS-CoV-2 infection. This condition, known as Long COVID (LC) or sometimes referred to as Post-COVID Condition (PCC) or post-acute sequelae of COVID-19, has emerged as a complex multisystemic condition and challenging health issue, affecting approximately 10% of COVID-19 patients. Various symptoms characterize LC, including fatigue, sleep disturbances, cognitive impairment, and mood disturbances. Some of the symptoms are shared with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) - a condition marked by debilitating fatigue and a host of other symptoms without precise biomarkers or objective tests for diagnosis. Effective LC treatments remain elusive and LC patients continue to grapple with persistent symptoms that significantly impact their quality of life. Given the lack of effective treatments, it is imperative to explore novel therapeutic approaches that may alleviate the suffering of this patient population.
Trial Details
NCT Number NCT06721949
Lead Sponsor University of Alberta
Collaborators: Canadian Institutes of Health Research (CIHR), University Health Network, Toronto
Conditions
(from sponsor)
Long COVID
Related terms Post-Acute COVID-19 Syndrome
Enrollment 300 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov