Mindfulness And Placebo for Pain (MAPP) Study

This study proposes a three-arm randomized-controlled trial (RCT) that evaluates the feasibility and acceptability of combining a mindfulness-based therapy (MBT) and open-label placebo (OLP) treatment for individuals with chronic pain. Individuals with chronic pain will be recruited to participate in an 8-week trial, with a subsequent 3-month post-treatment follow-up. Participants will be randomly assigned to one of the following three conditions: 1. Mindfulness-Based Stress Reduction (MBSR) 2. OLP treatment 3. combination of MBSR and OLP treatment

NCT Number	NCT06720909
Lead Sponsor	Arizona State University Collaborators: National Center for Complementary and Integrative Health (NCCIH)
Conditions	Chronic Pain
Enrollment	45 participants
Start Date	2025-01-27
Primary Completion	2027-03-01 (estimated)
Study Completion	2027-03-01 (estimated)
Updated on ClinicalTrials.gov	2026-07-24