Tissue Analysis of Liver Grafts as a Predictor of Transplant Outcome.

Despite the good clinical results in terms of outcome with the application of HOPE prior to liver transplantation, very little is still known about the phenotypic and molecular changes that occur during perfusion/preservation during HOPE, particularly with regard to endothelial trophism and activation. Delving into these aspects would be very useful to allow personalised perfusion treatments in the future, thus improving the outcome of transplantation.

NCT Number	NCT06717542
Lead Sponsor	IRCCS Azienda Ospedaliero-Universitaria di Bologna
Conditions	Hepatic Transplantation, Rejection; Transplant, Liver
Enrollment	200 participants
Start Date	2023-01-17
Primary Completion	2027-07 (estimated)
Study Completion	2028-01 (estimated)
Updated on ClinicalTrials.gov	2024-12-05