Comparison of Pregnancy Outcomes in Women with Polycystic Ovarian Syndrome with and Without Glucophage

The goal of this clinical trial is to learn if Glucophage (metformin) improves pregnancy outcomes in women with polycystic ovarian syndrome (PCOS). It will also evaluate the safety of Glucophage during pregnancy. The main questions it aims to answer are: Does Glucophage reduce the risks of early pregnancy loss, preterm delivery, and gestational diabetes? Are there any medical problems associated with taking Glucophage during pregnancy? Researchers will compare Glucophage with standard care (diet and exercise) to see if it improves pregnancy outcomes in women with PCOS. Participants will: Take Glucophage or follow a standard diet and exercise plan throughout pregnancy. Attend regular follow-up visits for checkups, ultrasounds, and blood tests. Have their pregnancy outcomes, such as fetal growth and gestational diabetes, recorded.

NCT Number	NCT06713967
Lead Sponsor	University of Health Sciences Lahore
Conditions	Polycystic Ovarian Syndrome (PCOS), Pregnancy Outcomes
Enrollment	70 participants
Start Date	2025-02-02
Primary Completion	2025-05-25 (estimated)
Study Completion	2025-05-26 (estimated)
Updated on ClinicalTrials.gov	2024-12-06