Clinical Trial

APPI-Cost Trial for Perforated Appendicitis

Recruiting Phase 4
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Record status
This record was last updated December 11, 2025 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
The purpose of this study to assess the clinical effectiveness and cost-effectiveness of povidone-iodine (PVI) irrigation in perforated appendicitis, to investigate barriers and facilitators to future implementation of PVI irrigation, and to collect costs and clinical and patient-reported outcomes among patients with non-perforated appendicitis.
Protocol Amendment History 6 amendments
This ClinicalTrials.gov record has been amended 6 times since 2024-11-22; most recent amendment 2025-12-04.
Status change: Not Yet Recruiting → Recruiting 2025-04-07
Trial Details
NCT Number NCT06705842
Lead Sponsor The University of Texas Health Science Center, Houston
Collaborators: National Center for Advancing Translational Sciences (NCATS)
Conditions Perforated Appendicitis
Enrollment 346 participants
Start Date 2025-04-07
Primary Completion 2026-06-30 (estimated)
Study Completion 2027-03-31 (estimated)
Updated on ClinicalTrials.gov 2025-12-11