Clinical Trial

Gabapentin and Pressor Response to Intubation

Not Yet Recruiting Phase 1/2
View on ClinicalTrials.gov →
Record status
This record was last updated November 26, 2024 (before its estimated June 15, 2025 completion). Its status may not reflect the trial's current state.
Summary
This study evaluates the effectiveness of oral gabapentin in reducing the pressor response (increased MAP, HR, and BP) during laryngoscopic intubation. It is a prospective, double-blind randomized controlled trial involving 144 patients undergoing elective surgery. Gabapentin 300 mg or placebo will be administered preoperatively, with hemodynamic parameters monitored before and after intubation. The study aims to determine if gabapentin attenuates the sympathetic stress response compared to placebo.
Trial Details
NCT Number NCT06705101
Lead Sponsor Liaquat National Hospital & Medical College
Conditions Elective Surgical Patients, Blood Pressure
Enrollment 144 participants
Start Date 2024-12-15
Primary Completion 2025-06-15 (estimated)
Study Completion 2025-07-16 (estimated)
Updated on ClinicalTrials.gov 2024-11-26