Research on Key Interventional Technologies for Controlling the Epidemic in High-prevalence Areas of Tuberculosis in Guangxi, China

The goal of this study is to find out if using mobile vans with advanced technology can help reduce tuberculosis (TB) in rural Guangxi, China. The study will also examine how practical and cost-effective this approach is. The main questions it aims to answer are: 1) Does this new screening method lower the number of TB cases among high-risk groups? and 2) Is this method practical and acceptable for communities and healthcare workers? Participants in the study will: 1) undergo TB screening with mobile vans that use artificial intelligence (AI) to read chest X-rays, 2) answer a short questionnaire about their symptoms and health history, and 3) provide sputum samples for GeneXpert testing if needed. Some communities will receive the new screening method, while others will continue with usual care. Researchers will compare TB rates in the two groups over three years to see if the new approach works better for TB control. If successful, this method could be used to improve TB control in other areas.

NCT Number	NCT06702774
Lead Sponsor	University of Toronto Collaborators: Guangxi Zhuang Autonomous Region Center for Disease Prevention and Control
Conditions	Tuberculosis (TB)
Enrollment	72,000 participants
Start Date	2021-11-20
Primary Completion	2025-01-31 (estimated)
Study Completion	2025-04-30 (estimated)
Updated on ClinicalTrials.gov	2024-12-06