Clinical Trial

INJECTABLE COLD ENERGY THERAPY FOR THE MANAGEMENT OF CHRONIC PAIN ASSOCIATED WITH OSTEOARTHRITIS OF THE KNEE

Study acronym: ICE
Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
The goal of this clinical trial is to evaluate the effectiveness of Neural Ice for pain management associated with knee osteoarthritis in adults aged 22-80 years. Participants will attend study visits and complete subject diaries. Participants will be followed for 6 months after study procedure.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2024-11-19; most recent amendment 2025-10-27.
Status change: Recruiting → Active, Not Recruiting 2025-10-27
Status change: Not Yet Recruiting → Recruiting 2024-12-17
Trial Details
NCT Number NCT06700109
Lead Sponsor Brixton Biosciences, Inc.
Conditions Osteoarthritis (OA) of the Knee
Enrollment 263 participants
Start Date 2024-11-19
Primary Completion 2027-02-01 (estimated)
Study Completion 2027-02-01 (estimated)
Updated on ClinicalTrials.gov 2025-10-28