Fertility Protection for Children, Adolescents and Young Adults

This study focuses on improving fertility preservation and long-term care for children, adolescents, and young adults (CAYA) undergoing cancer treatments or stem cell transplantation. These treatments can harm fertility, and ensuring that patients receive the right support and follow-up care is critical. The main study goals are: 1. Understanding Fertility Risks: Researchers aim to identify factors that predict fertility problems after cancer treatments, such as the type of therapy, hormone levels, body composition, or genetic predispositions. 2. Addressing Patient and Family Needs: The program will explore the concerns, needs, and challenges faced by young patients and their parents regarding fertility. It will also examine how these issues affect their quality of life. 3. Improving Clinical Care: Current practices in fertility preservation and counseling will be studied to identify gaps and improve care structures. To achieve these goals, the program will: * Create a database to collect and analyze medical data from patients before, during, and after cancer treatments. * Study the prevalence and long-term effects of fertility problems in young patients. * Document medical interventions like fertility preservation methods (e.g., freezing eggs or sperm) and treatments for late effects. * Assess patients' and families' fertility-related quality of life and their informational needs. Ultimately, the project aims to establish an interdisciplinary center to support fertility preservation and improve the quality of care for young patients facing cancer and its treatments.

NCT Number	NCT06692868
Lead Sponsor	University of Ulm Collaborators: German Federal Ministry of Education and Research
Conditions	Stem Cell Transplant, Stem Cell Transplantation, Oncological Outcomes, Oncological Patients, Oncological Children, Fertility, Fertility Protection, Endocrinological Late-effects +3 more
Enrollment	2,000 participants
Start Date	2024-12-09
Primary Completion	2044-11 (estimated)
Study Completion	2044-11 (estimated)
Updated on ClinicalTrials.gov	2025-01-16