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Electrolysed Saline Rinse as an Adjunct for Treatment of Chronic Periodontitis

Study acronym: EOSPERIO
StatusRecruiting
PhaseNot applicable
Started
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Record status
This record was last updated May 11, 2026 (before its estimated June 6, 2026 completion). Its status may not reflect the trial's current state.

Record History

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  1. Primary completion date: Dec 6, 2025 to Jun 6, 2026
    • Interventions: Electrolysed saline rinse (Other) to Chlorhexidine 0,12% (Device), Distilled water group (Device), Electrolysed saline rinse (Other)
    • Secondary endpoints: details revised at 1 of 3 entries
    • Study description revised
    v2
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The study will be conducted as a prospective, double-blind, parallel, randomized, placebo-controlled study at the Dental Clinic of University Medical Centre Ljubljana. It will involve a one-month test period, during which the test subjects will use either placebo, Electrolysed Oxidising Saline (EOS) or chlorhexidine (CHX) in the form of a mouthwash as an adjunct to the non-surgical treatment of chronic periodontitis (i.e. root planing and scaling). The study will include 60 subjects selected from consecutively scheduled patients referred by their personal dentists for periodontal treatment at the Dental Clinic of University Medical Centre Ljubljana.
Trial Details
NCT Number NCT06692582
Lead Sponsor University of Ljubljana
Conditions
(from sponsor)		 Periodontitis
Related terms Periodontitis
Enrollment 60 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov