Photobiomodulation and Tooth Analgesia

The purpose of this study is to test photobiomodulation (PBM) with a non-invasive light device for reducing discomfort during dental treatments in children. We plan to conduct a series of three clinical studies in 200 school-aged children requiring routine dental treatment. The first study aims to test if PBM works for tooth and soft tissue by assessing response to cold testing and probing of gums. The second study aims to test if use of PBM on soft tissues before injection reduces discomfort. The third study aims to test if PBM can be used to do simple dental fillings in baby teeth without numbing injection.

NCT Number	NCT06691269
Lead Sponsor	University of Maryland, Baltimore
Conditions	Dental Anaesthesia, Dental Pain, Dental Analgesia
Enrollment	200 participants
Start Date	2025-07-07
Primary Completion	2027-06 (estimated)
Study Completion	2027-06 (estimated)
Updated on ClinicalTrials.gov	2026-08-12