Clinical Trial

Conversion Surgery Vs. Palliative Care in Pancreatic Cancer Oligometastatic to the Liver

Study acronym: SONAR
Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
This study investigates the impact of surgical resection compared to palliative care in patients with oligometastatic pancreatic cancer limited to the liver. Specifically, it examines whether surgery after stable disease or response to chemotherapy can improve survival and quality of life. The international, multicenter randomized trial will recruit 56 patients, assigning them to either surgical resection (including tumor and liver metastases) or ongoing palliative care with chemotherapy. Stratification by performance status, tumor markers, and tumor location will ensure balanced study groups. Outcome assessments, conducted over a minimum two-year follow-up, include clinical evaluations, imaging, and quality-of-life metric
Trial Details
NCT Number NCT06690528
Lead Sponsor Azienda Ospedaliera di Padova
Collaborators: University of Padova
Conditions Pancreatic Cancer Metastatic
Enrollment 56 participants
Start Date 2024-11-06
Primary Completion 2028-11 (estimated)
Study Completion 2028-11 (estimated)
Updated on ClinicalTrials.gov 2024-11-15