Effects of Dexmedetomidine on Postoperative Neurocognitive Disorder

This prospective study involves assessing neurocognitive function in patients undergoing laparotomic gastrointestinal surgery. Mini Mental state Assessment test and Mini-Cog tests will be conducted at multiple intervals preoperatively and postoperatively. Anesthesia management, vital signs, drug consumption, and blood gas values will be recorded throughout the surgery. After all neurocognitive evaluations of the patients are performed at planned intervals for 1 week, the levels of dexmedetomidine and remifentanyl consumed by the patients in the peroperative period will be determined from the anesthesia follow-up sheet and the total duration and amount used will be recorded. At the end of the study, the relationship between neurocognitive values and dexmedetomidine will be compared.

NCT Number	NCT06689137
Lead Sponsor	Haseki Training and Research Hospital
Conditions	Neurocognitive Disorder, Dexmedetomidine Infusion, Postoperative Cognitive Dysfunction, Postoperative Cognitive Dysfunction(POCD), Laparoscopic Abdominal Surgery
Enrollment	80 participants
Start Date	2024-10-13
Primary Completion	2025-03-15 (estimated)
Study Completion	2025-06-15 (estimated)
Updated on ClinicalTrials.gov	2024-11-14