Correlation of Typical LBBB Mechanical Activation Pattern by 2D Strain Echocardiography With Acute GWE Improvement in Patients Receiving LBBp or Conventional BiVp for Cardiac Resynchronization Therapy (Echo LBBp)

The present study is a multicenter interventional non randomised study in patients requiring an implantable device for cardiac resynchronization therapy. Its primary objective is to investigate whether the presence of a specific echocardiographic contraction pattern before implantation is associated with increased rates of acute improvement in myocardial function (as measured by an ultrasound) and to compare the improvement in two groups of patients based on the type of pacing (biventricular or left-sided pacing)

NCT Number	NCT06689111
Lead Sponsor	University Hospital of Patras Collaborators: University General Hospital of Heraklion, Ippokrateio General Hospital of Thessaloniki, Onassis Cardiac Surgery Centre, Alexandra Hospital, Athens, Greece, Korgialenio-Benakio Red Cross Hospital, Ippokration General Hospital
Conditions	Heart Failure With Reduced Ejection Fraction (HFrEF)
Enrollment	100 participants
Start Date	2024-05-23
Primary Completion	2026-09-30 (estimated)
Study Completion	2026-11-30 (estimated)
Updated on ClinicalTrials.gov	2025-12-05