Cognitive Impact Associated With Surgery For Gastric Or Esophageal Cancer

The primary objective of this observational study is to investigate the incidence of Post Operative Delirium (POD) after gastroesophageal cancer surgery. Secondary objectives are to investigate the relationship between POD, preoperative depression, frailty, quality of life, malnutrition and sarcopenia. Participants identified with POD will be asked (at the routine follow-up meeting after surgery) to participate in an qualitative interview, in order to understand the participant's experience of postoperative delirium. The main objective aims to answer: What is the incidence of POD after gastroesophageal cancer surgery.

NCT Number	NCT06687291
Lead Sponsor	Karolinska Institutet Collaborators: Region Stockholm
Conditions	Gastroesophageal Cancer (GC), Postoperative Delirium (POD), Quality of Life (QOL), Frailty, Malnutrition, Sarcopenia, Chemobrain, Chemotherapy +1 more
Enrollment	130 participants
Start Date	2025-02-13
Primary Completion	2027-11-11 (estimated)
Study Completion	2028-11-11 (estimated)
Updated on ClinicalTrials.gov	2026-08-11