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Combined Use of PRP and Hyaluronic Acid for Infiltrative Treatment of Patients With Knee Osteoarthritis

StatusRecruiting
PhaseNot applicable
Started
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Record History

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  1. Trial status: Not Yet Recruiting to Recruiting
    • Study sites: 1 to 2
    • Start date changed from estimate of Dec 2025 to Dec 11, 2025
    v7
  2. Start date: Sep 2025 to Dec 2025v6
  3. Collaborators expanded, about 4 wordsv5
  4. Start date: Apr 2025 to Sep 2025v4
  5. Start date: Jan 2025 to Apr 2025v3
  6. Secondary endpoints: details revised at 5 of 14 entriesv2
  7. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
"PRP+HA-23" is a double-blind randomized controlled clinical trial with 1:1:1 allocation. The objective of the study is to evaluate by a randomized controlled, double-blind clinical trial the efficacy and safety of viscosupplementation-associated PRP infiltration compared with PRP-only or HA-only infiltration for the treatment of patients with knee osteoarthritis.
Trial Details
NCT Number NCT06685120
Lead Sponsor Istituto Ortopedico Rizzoli
Collaborators: University Hospital of Ferrara
Conditions
(from sponsor)		 Osteo Arthritis Knee
Enrollment 288 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov