Efficacy of Nerve Block Versus Botox in Chronic Migraine Management

The goal of this clinical trial is to determine whether nerve block injections (specifically, supratrochlear and greater occipital nerve injections) are as effective as Botulinum toxin A (Botox) injections in treating chronic migraine in adults. The main questions it aims to answer are: * Do nerve block injections reduce the number of monthly migraine days compared to baseline? * Are there any differences in the frequency of migraine-related symptoms between the nerve block and Botox treatment groups? * Which treatment leads to higher patient satisfaction and improved quality of life? Participants in this study will: * Receive either nerve block injections or Botox injections every 12 weeks. * Visit the clinic once every month for follow-ups and assessments. * Maintain a headache diary to record the frequency and severity of their migraines and any adverse effects experienced. * Researchers will compare the outcomes of the two groups to determine if one treatment is superior in terms of efficacy and patient satisfaction.

NCT Number	NCT06684249
Lead Sponsor	Zagazig University
Conditions	Chronic Migraine, Chronic Migraine, Headache
Enrollment	64 participants
Start Date	2024-11-10
Primary Completion	2025-05-10 (estimated)
Study Completion	2025-07-10 (estimated)
Updated on ClinicalTrials.gov	2024-11-12