The Impact of a Dexmedetomidine Perfusion on Intraoperative Remifentanil Consumption

Study acronym: DEXREM
StatusRecruiting
PhaseNot applicable
Started

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Trial flagged as At Risk
Primary completion moved at least 11 months later Nov 2025 → Nov 2026
See other at-risk trials from Ciusss de L'Est de l'Île de Montréal

Record History

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  1. Primary and study completion pushed from Nov 2025 to Nov 2026 Show 7 more changesShow less
    • Recruitment opened
    • Lead sponsor: Ciusss de L'Est de l'Île de Montréal to Ciusss de L'Est de l'Île de Montréal
    • Start date changed from estimate of Nov 2024 to May 9, 2025
    • Eligibility criteria expanded, about 7 words
    • Secondary endpoints: details revised at 6 of 14 entries
    • Site details revised
    • Publications: details revised at 1 of 1 entry
  2. Study First Submitted
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
Opioids analgesic are the gold standard for intraoperative pain management. Their short- and long-term adverse effect motivate anesthesiologists to explore opioid sparing strategies. Dexmedetomidine is a highly selective α2 adrenergic receptor agonist that could help minimize opioid consumption both intraoperative and postoperative due to its sedative, analgesic and sympatholytic properties. This new randomized controlled trial (RCT) will answer the question whether an intraoperative dexmedetomidine infusion compared to placebo has a clinically significant impact on intraoperative remifentanil consumption during a laparoscopic abdominal elective surgery.
Trial Details
NCT Number NCT06684197
Lead Sponsor Ciusss de L'Est de l'Île de Montréal
Conditions
(from sponsor)		 Dexmedetomidine, Total Intravenous Anesthesia, Remifentanil Consumption, Remifentanil, Laparoscopic Abdominal Surgery
Enrollment 72 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov