Impact of Intrahepatic Cholestasis of Pregnancy on Neonatal Respiratory Outcomes

Intrahepatic cholestasis of pregnancy is a liver condition in late pregnancy, causing itching and high bile acid levels that return to normal after birth. Babies born to mothers with this condition may have a higher risk of breathing issues. Researchers suspect bile acids might lead to a specific type of lung problem in newborns, but more studies are needed to confirm this.

NCT Number	NCT06679972
Lead Sponsor	Carol Davila University of Medicine and Pharmacy
Conditions	Intrahepatic Cholestasis of Pregnancy, Respiratory Distress Syndrome, Newborn
Enrollment	120 participants
Start Date	2024-10-28
Primary Completion	2027-12-10 (estimated)
Study Completion	2028-03-01 (estimated)
Updated on ClinicalTrials.gov	2026-02-18