Implementation of a Standardized Algorithm for Coronary Calcification With Plaque Modification

In this study, the doctors will follow a set of rules that is called an algorithm. An algorithm is a step-by-step approach that doctors use to guide them when making decisions about the best way to treat their patients. Algorithms are useful because they help doctors decide on the best treatment approach based on the patient's individual circumstances and the best medical evidence available. The algorithm that is being used in this study is called a calcium modification algorithm and it will guide doctors when deciding on the best way to modify or break up the calcium in coronary arteries. In this study, we aim to prove that the calcium modification algorithm, described above, safely and effectively guides doctors on the best way to modify calcium in patients' coronary arteries. By doing so, it will help doctors in making decisions about patients' treatment during their procedure. It will also help standardise care for patients, so patients receive the same treatment no matter what hospital they are in or what doctor is treating them.

NCT Number	NCT06678594
Lead Sponsor	Royal College of Surgeons, Ireland Collaborators: Cardiovascular Research Institute Dublin
Conditions	Myocardial Ischaemia, Severely Calcified Coronary Stenoses, Coronary Calcification
Enrollment	500 participants
Start Date	2024-09-24
Primary Completion	2026-03-23 (estimated)
Study Completion	2027-03-23 (estimated)
Updated on ClinicalTrials.gov	2024-11-07