Brachial Plexus Nerve Block Versus Haematoma Block for Closed Reduction of Distal Radius Fracture in Adults - The BLOCK Trial. A Multicentre Randomised Controlled Trial.

The aim of the project is to evaluate the beneficial and harmful effects of an ultrasound-guided brachial plexus nerve block for patients with a distal radius (wrist) fracture in the need of realignment of fractured bone endings without cutting the skin (closed reduction), in comparison to a haematoma block, which is standard care in Denmark. Every participant will receive one of the following types of anaesthesia for the realignment of the wrist fracture: 1. A nerve block of the arm (plexus brachialis block) 2. A haematoma block, which is the current standard anaesthesia in the emergency departments.

NCT Number	NCT06678438
Lead Sponsor	Nordsjaellands Hospital
Conditions	Distal Radius Fractures, Fracture Dislocation, Fracture Dislocation of Upper Limb Joint, Colles' Fracture, Closed Reduction of Fracture and Application of Plaster Cast
Enrollment	1,716 participants
Start Date	2024-12-10
Primary Completion	2026-11 (estimated)
Study Completion	2027-04 (estimated)
Updated on ClinicalTrials.gov	2025-06-17