Clinical Trial

A Prospective Cohort Study of Proton and Photon Therapy for Left-sided Breast Cancer.

Recruiting Phase 2
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Record status
This record was last updated May 30, 2025 (before its estimated July 31, 2026 completion). Its status may not reflect the trial's current state.
Summary
The goal of this study is to investigate the differences in toxicity and efficacy between proton and photon hypofractionated radiotherapy following lumpectomy or mastectomy for breast cancer. The main questions it aims to answer are: 1. What is the difference in the incidence of radiation-related grade 2 or higher adverse events within two years following proton versus photon therapy after breast-conserving surgery? 2. What is the difference in the incidence of radiation-related grade 2 or higher adverse events within two years following proton versus photon therapy after mastectomy?
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2024-11-05.
Trial Details
NCT Number NCT06677879
Lead Sponsor Shanghai Proton and Heavy Ion Center
Conditions Breast Cancer
Enrollment 780 participants
Start Date 2024-08-01
Primary Completion 2026-07-31 (estimated)
Study Completion 2028-07-31 (estimated)
Updated on ClinicalTrials.gov 2025-05-30