Effectiveness of Creatine on Pain, Fatigue, and Muscle Architectural Variables in Patients Witg Fibromyalgia.

Creatine, a non-protein organic amino acid, is synthesized from arginine, glycine, and methionine. The use of creatine has been shown to be effective in healthy subjects, providing benefits primarily in terms of strength, which has been the main factor studied. In patients with various conditions, including pain, creatine supplementation has demonstrated a reduction in pain and even cognitive improvements. Due to creatine's general improvement in muscular endurance and fatigue.

NCT Number	NCT06675708
Lead Sponsor	Camilo Jose Cela University
Conditions	Fibromyalgia
Enrollment	80 participants
Start Date	2025-02-12
Primary Completion	2026-05-30 (estimated)
Study Completion	2026-06-30 (estimated)
Updated on ClinicalTrials.gov	2026-07-29