Prolonged Exposure Therapy to Treat Posttraumatic Stress Disorder in Pregnant Patients

The goal of this clinical trial is to learn if a treatment for adults with PTSD called prolonged exposure + incentives (PE+) works to treat pregnant patients. The main question it aims to answer is: Does PE+ decrease PTSD symptoms? All participants will receive PE+ to see if their PTSD symptoms at the end of the trial are less than at the beginning. Participants will: * Receive individual PE+ therapy for 1 hour weekly for 12 weeks. * Receive financial incentives for attending each PE+ session. * Attend assessment visits every 4 weeks for the 12 weeks of the trial. * Allow research staff to collect some information about their labor and delivery from their medical records after their babies are born.

NCT Number	NCT06670079
Lead Sponsor	University of Vermont
Conditions	Posttraumatic Stress Disorder, Pregnancy
Enrollment	30 participants
Start Date	2026-02-05
Primary Completion	2027-07-15 (estimated)
Study Completion	2027-07-22 (estimated)
Updated on ClinicalTrials.gov	2026-05-13