Clinical Trial

Personalized Post-Operative Pain Management

Active, Not Recruiting Phase 4
View on ClinicalTrials.gov →
Record status
This record was last updated November 1, 2024 (before its estimated December 2025 completion). Its status may not reflect the trial's current state.
Summary
The main questions this study aims to answer are: Does perioperative PGx personalized opiate therapy reduce persistent post-operative opioid use dependency, improve pain management and reduce opiate related adverse events in opioid naïve patients after surgery? Participants will: Take hydromorphone if the PGx results determine they have a SNP indicating high or low metabolic activity in the CYP2D6 enzyme. Complete a 7-day pain diary post-discharge. Complete a follow-up phone call once per month for 90 days.
Trial Details
NCT Number NCT06669650
Lead Sponsor University of Tennessee Graduate School of Medicine
Conditions Persistent Post Operative Opioid Use, Post-surgical Pain
Enrollment 208 participants
Start Date 2024-09-25
Primary Completion 2025-12 (estimated)
Study Completion 2025-12 (estimated)
Updated on ClinicalTrials.gov 2024-11-01