Effect of Force Magnitude on Canine Retraction and Gingival Crevicular Fluid Proteome

This study aims to examine the effect of force levels in orthodontic treatment during canine retraction. Force levels refer to the pressure applied by the orthodontic devices to move teeth. Data collection will include gingival fluid, dental molds from a digital scanner, and x-rays of the upper canine region on both sides of the mouth during treatment. The null hypothesis to be tested is that there is no significant difference in the rate of canine movement between the light force and the heavy force levels.

NCT Number	NCT06668194
Lead Sponsor	UConn Health Collaborators: Charles Burstone Foundation
Conditions	Tooth Crowding
Enrollment	40 participants
Start Date	2024-11-13
Primary Completion	2027-10-01 (estimated)
Study Completion	2028-04-01 (estimated)
Updated on ClinicalTrials.gov	2024-11-26