Clinical Trial

Association Between P0.1 and Extubation Failure in Adult Patients With Acute Hypoxemic Respiratory Failure. A Multicenter Prospective Cohort Study

Active, Not Recruiting
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Record status
This record was last updated October 28, 2024 (before its estimated August 29, 2025 completion). Its status may not reflect the trial's current state.
Summary
The goal of this observational study is to learn about the effect of the occlusion pressure during the first 100 miliseconds (P01) over the extubation failure in participants receiving mechanical ventilation for acute respiratory failure. The main question it aims to answer is: Are high P0.1 values (≥3 cmH2O) measured 30 minutes after starting a spontaneous breathing trial associated with extubation failure in adult patients who were intubated for acute hypoxemic respiratory failure?
Trial Details
NCT Number NCT06662201
Lead Sponsor Argentinian Intensive Care Society
Conditions Ventilator Weaning
Enrollment 256 participants
Start Date 2024-08-29
Primary Completion 2025-08-29 (estimated)
Study Completion 2025-08-29 (estimated)
Updated on ClinicalTrials.gov 2024-10-28