Fungal Ulcer Treatment Augmented With Natamycin and Cyclosporine A

The goal of this clinical trial is to learn if adjunctive topical Cyclosporine A eye drops combined with standard of care topical Natamycin treatment improves vision outcomes in patients with fungal keratitis.

NCT Number	NCT06658002
Lead Sponsor	University of California, San Francisco Collaborators: Aravind Eye Hospitals, India, Aravind Eye Care System
Conditions	Fungal Keratitis, Corneal Ulcer
Enrollment	150 participants
Start Date	2025-09-01
Primary Completion	2027-09-01 (estimated)
Study Completion	2027-09-01 (estimated)
Updated on ClinicalTrials.gov	2026-06-05