Feasibility and Safety of Early Mobilization and Rehabilitation in Intensive Care Unit Patients

Intensive Care Unit Acquired Weakness (ICU-AW) is a common complication of critical illnesses, occurring in approximately 50% of ICU patients and is strongly associated with increased morbidity, physical impairments, and both short- and long-term mortality. The main characteristics of ICU-AW are symmetrical generalised muscle weakness affecting both respiratory and limb muscles; however, the clinical phenotype may differ depending on age, disease burden, length of ICU stay, and mechanical ventilation duration. The objective of the present study is to evaluate the feasibility achieved and the safety outcomes reported in a cohort of critically ill patients who undergo early mobilisation and rehabilitation in intensive care units. This research is a multicentre prospective cohort study.

NCT Number	NCT06653998
Lead Sponsor	Claudia Aristizábal
Conditions	Intensive Care Unit Acquired Weakness, Intensive Care Unit Patients
Enrollment	220 participants
Start Date	2024-05-10
Primary Completion	2025-03 (estimated)
Study Completion	2025-04 (estimated)
Updated on ClinicalTrials.gov	2024-10-23