Clinical Trial

Pharmacokinetics of Oral Calcium Carbonate in Parturients

Completed Early Phase 1
View on ClinicalTrials.gov →
Summary
This study investigates the time course of change in calcium in the blood after a pregnant subject takes an oral dose of calcium carbonate (commonly marketed as "Tums"). Midway through the trial, with IRB permission, the oral calcium formulation was switched to calcium citrate to test whether this, better-absorbed formulation might prove more effective in increasing serum calcium. This information is important for trials investigating whether oral calcium can reduce postpartum hemorrhage, bleeding after delivery.
Protocol Amendment History 5 changes
critical Completed without a posted recruiting period 2026-08-13
notable Enrollment reduced: 60 -> 20 participants 2026-08-13
minor Trial arms changed: 1 -> 2 2026-08-13
notable Primary completion pushed: 2025-08 -> 2025-10-11 2026-08-13
minor Completion pushed: 2025-10 -> 2025-12-03 2026-08-13
Trial Details
NCT Number NCT06650930
Lead Sponsor Stanford University
Conditions Pregnancy, Pharmacokinetics, Postpartum Hemorrhage
Enrollment 20 participants
Start Date 2025-01-23
Primary Completion 2025-10-11 (estimated)
Study Completion 2025-12-03 (estimated)
Updated on ClinicalTrials.gov 2026-08-12