20-25 Year Follow-Up on Regenerative Bone Procedures for Peri-Implantitis

The goal of this 20-25-year observational study is to investigate the outcomes of bone regenerative surgery in peri-implantitis. Two different techniques will be compared: surgery with a bone substitute alone and surgery with a bone substitute combined with a membrane, to determine their effectiveness and assess whether one is more effective than the other. The intention of this observational study is to learn more about the long-term effects of bone regenerative surgery in patients with peri-implantitis. Patients will be called in for a clinical and radiographic examination of the surgically treated implant(s). Probing pocket depths, presence of pus, bleeding around the implant (s) and a radiograph of the implant (s). To be able to compare with the 1, 3, 5 and 10 year measurements.

NCT Number	NCT06648564
Lead Sponsor	Kristianstad University
Conditions	Peri-implantitis
Enrollment	20 participants
Start Date	2025-08-31
Primary Completion	2026-12-31 (estimated)
Study Completion	2027-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-06-29