Clinical Trial

Human Papillomavirus Association and Genomic Exploration in Head-Neck Squamous Cell Carcinomas

Study acronym: HPV & HNSCC
Recruiting
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Record status
This record was last updated December 31, 2024 (before its estimated March 30, 2025 completion). Its status may not reflect the trial's current state.
Summary
Head and neck squamous cell carcinoma (HNSCC) represents a significant public health burden in Bangladesh with a high incidence and mortality rate. While traditional risk factors like tobacco and betel nut chewing contribute to HNSCC incidence, the emergence of HPV-associated HNSCC presents a unique challenge. The main goal of this observational study is to explore the prevalence, risk factors, and biological mechanisms underlying food habits and HPV-driven HNSCC in the population and identify the genomic changes and characteristics related to this malignancy. This study will provide the prevalence of HPV-associated HNSCC and screening the HPV typing in the Bangladeshi population, identify risk factors, and any biologically driven mechanisms causing HNSCC.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2024-10-12.
Trial Details
NCT Number NCT06642324
Lead Sponsor Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Conditions Head Neck Cancer, Oropharyngeal Neoplasms
Enrollment 550 participants
Start Date 2024-04-30
Primary Completion 2025-03-30 (estimated)
Study Completion 2025-09-30 (estimated)
Updated on ClinicalTrials.gov 2024-12-31