Clinical Trial

Bronchoscopic Lung Volume Reduction in Management of Localized Emphysema

Recruiting
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Record status
This record was last updated May 29, 2025 (before its estimated December 1, 2025 completion). Its status may not reflect the trial's current state.
Summary
Emphysema is a progressive phenotype of chronic Obstructive Pulmonary Disease (COPD), poses a significant global health burden characterized by irreversible lung parenchymal destruction and airspace enlargement. In recent years, bronchoscopic lung volume reduction (BLVR) has considerable interest as a minimally invasive approach to reducing hyperinflation and improving lung function in patients with emphysema. BLVR techniques aim to achieve lung volume reduction by occluding or ablating emphysematous lung tissue through endobronchial delivery of various agents. Many techniques are available for BLVR as coil, endo-bronchial valve, and biological as thrombin, autologous blood and chemicals as silver nitrate solution.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2024-10-03.
Trial Details
NCT Number NCT06629558
Lead Sponsor Mansoura University Hospital
Conditions Bronchoscopic Lung Volume Reduction
Enrollment 30 participants
Start Date 2024-10-01
Primary Completion 2025-12-01 (estimated)
Study Completion 2026-03-01 (estimated)
Updated on ClinicalTrials.gov 2025-05-29