Rapid Point-of-care Bacteriuria and Microbial Susceptibility for Women With Suspected Uncomplicated Urinary Tract Infections: Diagnostic Accuracy in General Practice.

In this study, adult women presenting at their general practitioner with a likely bladder infection (with symptoms like a burning sensation when urinating, pain in the lower abdomen, and frequent or urgent need to urinate) will be invited. After informed consent, women provide a urine sample, which is tested using a new system called the PA-100-AST (from the manufacturer Sysmex). This point-of-care test showed first evidence to be able to quickly detect the presence of bacteria commonly responsible for bladder infections. If bacteria are found, the test also checks which antibiotics may work best to treat the infection. Additionally, a sample of the urine is sent to a lab for a traditional culture test, which is considered the most accurate method. The goal of this study is to compare the accuracy of the PA-100-AST system to the lab-based test to see how well it works in general practice.

NCT Number	NCT06625268
Lead Sponsor	Wuerzburg University Hospital Collaborators: Jena University Hospital
Conditions	Urinary Tract Infection (Diagnosis)
Enrollment	200 participants
Start Date	2024-08-01
Primary Completion	2025-04-30 (estimated)
Study Completion	2025-04-30 (estimated)
Updated on ClinicalTrials.gov	2025-02-17