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Bleeding Prevention With Desmopressin for Allograft Kidney Biopsies

Study acronym: BRIDGE
StatusEnrolling by Invitation
PhasePhase 4
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated September 11, 2025 (before its estimated June 2026 completion). Its status may not reflect the trial's current state.

Record History

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  1. Study title shortened, about 4 wordsv3
  2. Study title shortened, about 3 wordsv2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The goal of this study is to evaluate the efficacy and safety of desmopressin to prevent bleeding after percutaneous renal graft biopsy in patients at high risk of bleeding. Researchers will compare desmopressin (DDAVP) to placebo to see if the drug reduces the risk of bleeding events related to kidney biopsy. Participants will receive intravenous desmopressin medication (100ml) or placebo (100mL of saline solution) before the kidney biopsy.
Trial Details
NCT Number NCT06622187
Lead Sponsor Hospital de Clinicas de Porto Alegre
Conditions
(from sponsor)		 Bleeding, Transplant, Kidney, Desmopressin, Kidney Biopsy
Related terms Hemorrhage
Enrollment 96 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov