Clinical Trial

A Clinical Trial Evaluating the Safety and Efficacy of Intravenous HNF4α SrRNA in Treating Metastatic CRC Patients

Recruiting Early Phase 1
View on ClinicalTrials.gov →
Record status
This record was last updated April 24, 2025 (before its estimated July 2026 completion). Its status may not reflect the trial's current state.
Summary
This trial is a single-arm, open-label, exploratory first-in-human clinical study designed to evaluate the safety and tolerability of HNF4α srRNA injection in patients with locally unresectable or metastatic colorectal cancer, and to preliminarily explore its effectiveness in treating metastatic colorectal cancer.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2024-09-27; most recent amendment 2025-04-21.
Status change: Not Yet Recruiting → Recruiting 2025-04-19
Trial Details
NCT Number NCT06621173
Lead Sponsor Shanghai Changzheng Hospital
Conditions Metastatic Colorectal Cancer (mCRC)
Enrollment 9 participants
Start Date 2024-11-12
Primary Completion 2026-07 (estimated)
Study Completion 2026-09 (estimated)
Updated on ClinicalTrials.gov 2025-04-24