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Efficacy and Safety of Thalidomide Combined With Glutamine in the Treatment of Radiation Intestinal Injury.

StatusRecruiting
PhasePhase 2
Started
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Record History

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  1. Notable Trial status: Not Yet Recruiting to Recruiting
    • Primary completion date: Oct 1, 2025 to Oct 1, 2028
    • Study sites: 0 to 1
    • Study completion date: Oct 1, 2026 to Nov 1, 2028
    v3
  2. Minor Eligibility criteria shortened, about 14 words
    • Study title shortened, about 6 words
    v2
  3. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
7 trials monitored
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At present, there is still a lack of standard and effective treatment strategies and procedures for radiation intestinal injury. Studies have shown that thalidomide can effectively treat refractory gastrointestinal bleeding caused by vascular malformation. Therefore, The investigators designed a single-center, open-label, randomized controlled study to evaluate the efficacy and safety of thalidomide combined with glutamine in the treatment of radiation intestinal injury.
Trial Details
NCT Number NCT06617182
Lead Sponsor Yongquan Shi
Conditions
(from sponsor)
Radiation Enteritis
Enrollment 150 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov