Clinical Trial

A Real-World Evidence Study of Goniotomy With the C-REX™ Instrument in Patients With Primary Open Angle Glaucoma

Study acronym: CIRCLE
Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
This study enrolls adults with primary open angle glaucoma (POAG) who underwent goniotomy intraocular pressure (IOP)-lowering surgery with the C-Rex Instrument. Patients are consented prior to surgery and followed for 12 months postoperatively. Data regarding IOP, use of glaucoma medications, and any device-related complications are collected during the study time period.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2024-09-24; most recent amendment 2026-07-18.
Status change: Recruiting → Active, Not Recruiting 2026-07-18
Trial Details
NCT Number NCT06615661
Lead Sponsor Iantrek, Inc.
Conditions Primary Open Angle Glaucoma (POAG)
Enrollment 100 participants
Start Date 2024-08-14
Primary Completion 2026-12 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2026-07-21