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Analysis of the Loss of Muscle Force, Power and Motor Control to Predict the Risk of Falls in Patients With Knee OA

Study acronym: PowerAGING
StatusRecruiting
PhaseNot applicable
Started
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Record status
This record was last updated February 27, 2026 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.

Record History

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  1. Primary completion date: Jun 30, 2025 to Jun 30, 2026
    • Primary endpoints: 6 to 4
    • Secondary endpoints expanded, about 5 words
    • Study title shortened, about 2 words
    v4
  2. Trial status: Not Yet Recruiting to Recruiting
    • Primary completion date: Apr 1, 2025 to Jun 30, 2025
    • Start date changed from estimate of Feb 1, 2025 to Jan 30, 2025
    • Site details revised
    v3
  3. Start date: Nov 1, 2024 to Feb 1, 2025v2
  4. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The twofold goal of this study is to understand the link between muscle power, muscle strength, and muscle control degradation with the risk of falling, and to develop a framework for the comprehensive and quantitative assessment of muscle power (and strength) in an elderly population of patients with knee osteoarthritis, who are at higher risk of falling. The main question it aims to answer is: ● Are muscle power and motor control degradation better predictors of falls than muscle strength in the aging population? Participants will undergo: * Muscle force assessment on a dynamometer * Muscle power assessment on a dynamometer and on isntrumented stairs * Home-based mobility monitoring * Full lower limb MRI acquisition * Gait assessment
Trial Details
NCT Number NCT06611618
Lead Sponsor Istituto Ortopedico Rizzoli
Conditions
(from sponsor)		 Knee Osteoarthritis (Knee OA), Falls Prevention
Related terms Osteoarthritis, Knee
Enrollment 50 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov