Clinical Trial

The Role of Regular Physical Activity in Enhancing Metabolic Health, Reducing Inflammation, and Improving Gut Function

Enrolling by Invitation
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Summary
The goal of this clinical trial is to learn if regular physical activity can improve metabolic health, reduce inflammation, and decrease gut permeability in individuals aged 50 and older. The main questions it aims to answer are: Does regular physical activity, even at low intensity, improve metabolic parameters? Does physical activity reduce inflammation and gut permeability in older adults? Researchers will compare a group participating in low-intensity dance classes to a group participating in higher-intensity calisthenics training to see if the intensity of exercise has different effects on these outcomes. Participants will be asked to: Attend organized training sessions led by instructors twice a week for 12 months. Complete anthropometric measurements (height, weight) and body composition analysis (DXA scan). Provide blood samples for biochemical analysis (glucose, insulin, CRP, etc.). Submit stool samples for gut health markers (calprotectin, zonulin, etc.). Complete surveys on lifestyle and dietary habits before and after the study.
Trial Details
NCT Number NCT06606678
Lead Sponsor Poznan University of Physical Education
Conditions Intestinal Inflammation, Metabolic Disease
Enrollment 400 participants
Start Date 2024-09-17
Primary Completion 2026-12-31 (estimated)
Study Completion 2027-06-30 (estimated)
Updated on ClinicalTrials.gov 2024-09-23