Effect of Acupuncture for Rapid Eye Movement Sleep Behavior Disorder

Rapid eye movement (REM) sleep behaviour disorder (RBD) is a parasomnia that is characterized by abnormal behaviours occurring during REM sleep（a sleep stage）, often as dream enactments that can cause injury. Treatment options are limited. Pharmacological treatments include melatonin and clonazepam, but they have varying degrees of adverse reactions. Acupuncture is a green and safe means of treatment and has therapeutic value in sleep disorders. Using the theory of traditional Chinese medicine, the acupuncture treatment of RBD group points was formulated, and good clinical effect was obtained in the early clinical practice.This study was designed to explore the clinical efficacy of acupuncture in the treatment of RBD. Thirty patients with RBD who met the inclusion and exclusion criteria were randomly divided into acupuncture group and sham acupuncture group, and were subjected to a 2-week screening period, a 4-week treatment period, and a 2-week follow-up period.The investigators will primarily observe whether there is a reduction in the number of weekly RBD events recorded by the wCIRUS-RBD questionnaire before and after treatment, and the reduction in the RWA index recorded by video polysomnography (vPSG).

NCT Number	NCT06606418
Lead Sponsor	Beijing Hospital of Traditional Chinese Medicine
Conditions	Rapid Eye Movement Sleep Behavior Disorder
Enrollment	30 participants
Start Date	2024-09-25
Primary Completion	2025-04-15 (estimated)
Study Completion	2025-04-30 (estimated)
Updated on ClinicalTrials.gov	2024-09-23